EFFECT OF NAPTHOXAZOLE DERIVATIVES i.e., 4-(1, 3-benzoxazol-2-yl)-2- phenylnaphtho[1, 2-d] [1, 3] OXAZOLE ON Salmonella typhoid

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Published: 01/10/2018

Article Number: 050201

Access Type: Full Article

Article Type: Original Research

Page: 222-227

Issue: 2018 - Volume 5 [Issue 2]

EFFECT OF NAPTHOXAZOLE DERIVATIVES i.e., 4-(1, 3-benzoxazol-2-yl)-2- phenylnaphtho[1, 2-d] [1, 3] OXAZOLE ON Salmonella typhoid

R. Kumar^a M. K. Singh ^bR. R. Kumar ^c

a Department of Chemistry, Patna University, Patna- 800005, Bihar, India

b Rastrakavi Ramdhari Singh Dinkar College of Engineering, Begusarai, Bihar, India

c Shershah Engineering College, Sasaram, Bihar, India

Received: 23-02-2018, Revised: 27-03-2018, Accepted: 20-04-2018, Available online: 01-10-2018

Abstract

Naphthoxazole derivatives i.e., 3-(1,3-benzoxazol-2-yl) naphthalen-2-ol was synthesized at 130– 135⁰C in the presence of PCl₃ from 3-hydroxynaphthalene-2-carboxylic acid and 2-amino phenol in chlorobenzene. These compounds were characterized by mass spectra, FT-IR and elemental analysis. Antibiotics activity of these compounds was analyzed against Salmonella typhi by using serial dilution method.

Keywords: Naphthoxazole, Antibiotic activity, Salmonella typhi, Mass spectra

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How to Cite

Kumar, R., Singh , M. K., Kumar , R. R. (2018). EFFECT OF NAPTHOXAZOLE DERIVATIVES i.e., 4-(1, 3-benzoxazol-2-yl)-2- phenylnaphtho[1, 2-d] [1, 3] OXAZOLE ON Salmonella typhoid. International Journal of Basic & Applied Science Research (IJBASR), 5 (2), 222-227